Facilitation of Th1-mediated immune response by prostaglandin E receptor EP1

Prostaglandin E(2) (PGE(2)) exerts its actions via four subtypes of the PGE receptor, EP1–4. We show that mice deficient in EP1 exhibited significantly attenuated Th1 response in contact hypersensitivity induced by dinitrofluorobenzene (DNFB). This phenotype was recapitulated in wild-type mice by ad...

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Main Authors: Nagamachi, Miyako, Sakata, Daiji, Kabashima, Kenji, Furuyashiki, Tomoyuki, Murata, Takahiko, Segi-Nishida, Eri, Soontrapa, Kitipong, Matsuoka, Toshiyuki, Miyachi, Yoshiki, Narumiya, Shuh
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2007
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118516/
https://ncbi.nlm.nih.gov/pubmed/17967902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20070773
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