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Dual roles of PGE(2)-EP4 signaling in mouse experimental autoimmune encephalomyelitis
Experimental autoimmune encephalomyelitis (EAE) is an animal model of multiple sclerosis (MS). Although prostaglandin (PG) concentrations are increased in cerebrospinal fluid of MS patients, the role of PGs in MS is unknown. We examined this issue by subjecting mice deficient in each PG receptor typ...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2901475/ https://ncbi.nlm.nih.gov/pubmed/20566843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0915112107 |
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