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Neuroprotective Role of Prostaglandin PGE(2) EP2 Receptor in Hemin-mediated Toxicity

Heme (Fe(2+) protoporphyrin IX) and hemin (Fe(3+)), the prosthetic group of hemoprotein, are cytotoxic due to their ability to contribute to the production of reactive oxygen species, increased intracellular calcium levels and stimulate glutamate mediated-excitotoxicity. Previous work by our group s...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Neurotoxicology
Asıl Yazarlar: Mohan, Shekher, Narumiya, Shuh, Doré, Sylvain
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4681391/
https://ncbi.nlm.nih.gov/pubmed/25451967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2014.10.012
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