Role of the Prostaglandin E(2) EP1 Receptor in Traumatic Brain Injury

Brain injuries promote upregulation of so-called proinflammatory prostaglandins, notably prostaglandin E(2) (PGE(2)), leading to overactivation of a class of its cognate G-protein-coupled receptors, including EP1, which is considered a promising target for treatment of ischemic stroke. However, the...

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Udgivet i:PLoS One
Main Authors: Glushakov, Alexander V., Fazal, Jawad A., Narumiya, Shuh, Doré, Sylvain
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245217/
https://ncbi.nlm.nih.gov/pubmed/25426930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113689
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