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Role of the Prostaglandin E(2) EP1 Receptor in Traumatic Brain Injury

Brain injuries promote upregulation of so-called proinflammatory prostaglandins, notably prostaglandin E(2) (PGE(2)), leading to overactivation of a class of its cognate G-protein-coupled receptors, including EP1, which is considered a promising target for treatment of ischemic stroke. However, the...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Glushakov, Alexander V., Fazal, Jawad A., Narumiya, Shuh, Doré, Sylvain
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245217/
https://ncbi.nlm.nih.gov/pubmed/25426930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113689
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