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Stimulation of Prostaglandin E(2)-EP3 Receptors Exacerbates Stroke and Excitotoxic Injury
The effect of PGE(2) EP3 receptors on injury size was investigated following cerebral ischemia and induced excitotoxicity in mice. Treatment with the selective EP3 agonist ONO-AE-248 significantly and dose-dependently increased infarct size in the middle cerebral artery occlusion model. In a separat...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1914218/ https://ncbi.nlm.nih.gov/pubmed/17275922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2006.12.012 |
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