Dual roles of PGE(2)-EP4 signaling in mouse experimental autoimmune encephalomyelitis

Experimental autoimmune encephalomyelitis (EAE) is an animal model of multiple sclerosis (MS). Although prostaglandin (PG) concentrations are increased in cerebrospinal fluid of MS patients, the role of PGs in MS is unknown. We examined this issue by subjecting mice deficient in each PG receptor typ...

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Hlavní autoři: Esaki, Yoshiyasu, Li, Youxian, Sakata, Daiji, Yao, Chengcan, Segi-Nishida, Eri, Matsuoka, Toshiyuki, Fukuda, Kazuhiko, Narumiya, Shuh
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901475/
https://ncbi.nlm.nih.gov/pubmed/20566843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0915112107
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