The prostaglandin receptor EP4 suppresses colitis, mucosal damage and CD4 cell activation in the gut

We used mice deficient in each of the eight types and subtypes of prostanoid receptors and examined the roles of prostanoids in dextran sodium sulfate–induced (DSS-induced) colitis. Among the prostanoid receptor–deficient mice, only EP4-deficient mice and not mice deficient in either DP, EP1, EP2, E...

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Autors principals: Kabashima, Kenji, Saji, Tomomi, Murata, Takahiko, Nagamachi, Miyako, Matsuoka, Toshiyuki, Segi, Eri, Tsuboi, Kazuhito, Sugimoto, Yukihiko, Kobayashi, Takuya, Miyachi, Yoshiki, Ichikawa, Atsushi, Narumiya, Shuh
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2002
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC150928/
https://ncbi.nlm.nih.gov/pubmed/11927615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14459
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