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Prostaglandin E(2)-EP2 signaling as a node of chronic inflammation in the colon tumor microenvironment

BACKGROUND: Colorectal cancer is the third most common cancer. Involvement of prostaglandin (PG) system in the pathogenesis of colorectal cancer has been suggested from clinical studies demonstrating therapeutic effect of NSAIDs including aspirin or selective COX-2 inhibitors. However, mechanisms on...

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Bibliografiske detaljer
Udgivet i:Inflamm Regen
Main Authors: Aoki, Tomohiro, Narumiya, Shuh
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725845/
https://ncbi.nlm.nih.gov/pubmed/29259703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41232-017-0036-7
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