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Prostaglandin E(2)-EP2 signaling as a node of chronic inflammation in the colon tumor microenvironment

BACKGROUND: Colorectal cancer is the third most common cancer. Involvement of prostaglandin (PG) system in the pathogenesis of colorectal cancer has been suggested from clinical studies demonstrating therapeutic effect of NSAIDs including aspirin or selective COX-2 inhibitors. However, mechanisms on...

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Detalhes bibliográficos
Publicado no:Inflamm Regen
Main Authors: Aoki, Tomohiro, Narumiya, Shuh
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725845/
https://ncbi.nlm.nih.gov/pubmed/29259703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41232-017-0036-7
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