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Prostaglandin E(2)-EP2 signaling as a node of chronic inflammation in the colon tumor microenvironment

BACKGROUND: Colorectal cancer is the third most common cancer. Involvement of prostaglandin (PG) system in the pathogenesis of colorectal cancer has been suggested from clinical studies demonstrating therapeutic effect of NSAIDs including aspirin or selective COX-2 inhibitors. However, mechanisms on...

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Publicat a:Inflamm Regen
Autors principals: Aoki, Tomohiro, Narumiya, Shuh
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725845/
https://ncbi.nlm.nih.gov/pubmed/29259703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41232-017-0036-7
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