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Prostaglandin E(2)-EP2 signaling as a node of chronic inflammation in the colon tumor microenvironment

BACKGROUND: Colorectal cancer is the third most common cancer. Involvement of prostaglandin (PG) system in the pathogenesis of colorectal cancer has been suggested from clinical studies demonstrating therapeutic effect of NSAIDs including aspirin or selective COX-2 inhibitors. However, mechanisms on...

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Bibliografische gegevens
Gepubliceerd in:Inflamm Regen
Hoofdauteurs: Aoki, Tomohiro, Narumiya, Shuh
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725845/
https://ncbi.nlm.nih.gov/pubmed/29259703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41232-017-0036-7
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