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Prostaglandin E(2)-EP2 signaling as a node of chronic inflammation in the colon tumor microenvironment

BACKGROUND: Colorectal cancer is the third most common cancer. Involvement of prostaglandin (PG) system in the pathogenesis of colorectal cancer has been suggested from clinical studies demonstrating therapeutic effect of NSAIDs including aspirin or selective COX-2 inhibitors. However, mechanisms on...

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Publicado en:Inflamm Regen
Autores principales: Aoki, Tomohiro, Narumiya, Shuh
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725845/
https://ncbi.nlm.nih.gov/pubmed/29259703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41232-017-0036-7
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