Sensitization of TRPV1 by EP(1 )and IP reveals peripheral nociceptive mechanism of prostaglandins

Prostaglandin E(2 )(PGE(2)) and prostaglandin I(2 )(PGI(2)) are major inflammatory mediators that play important roles in pain sensation and hyperalgesia. The role of their receptors (EP and IP, respectively) in inflammation has been well documented, although the EP receptor subtypes involved in thi...

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Autores principales: Moriyama, Tomoko, Higashi, Tomohiro, Togashi, Kazuya, Iida, Tohko, Segi, Eri, Sugimoto, Yukihiko, Tominaga, Tomoko, Narumiya, Shuh, Tominaga, Makoto
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2005
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1074353/
https://ncbi.nlm.nih.gov/pubmed/15813989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-1-3
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