Sensitization of TRPV1 by EP(1 )and IP reveals peripheral nociceptive mechanism of prostaglandins

Prostaglandin E(2 )(PGE(2)) and prostaglandin I(2 )(PGI(2)) are major inflammatory mediators that play important roles in pain sensation and hyperalgesia. The role of their receptors (EP and IP, respectively) in inflammation has been well documented, although the EP receptor subtypes involved in thi...

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Bibliographic Details
Main Authors: Moriyama, Tomoko, Higashi, Tomohiro, Togashi, Kazuya, Iida, Tohko, Segi, Eri, Sugimoto, Yukihiko, Tominaga, Tomoko, Narumiya, Shuh, Tominaga, Makoto
Format: Artigo
Language:Inglês
Published: BioMed Central 2005
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1074353/
https://ncbi.nlm.nih.gov/pubmed/15813989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-1-3
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