Abortive expansion of the cumulus and impaired fertility in mice lacking the prostaglandin E receptor subtype EP(2)

Female mice lacking the gene encoding the prostaglandin (PG) E(2) receptor subtype EP(2) (EP(2)(−/−)) become pregnant and deliver their pups at term, but with a much reduced litter size. A decrease in ovulation number and a much reduced fertilization rate were observed in EP(2)(−/−) females without...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Hizaki, Hiroko, Segi, Eri, Sugimoto, Yukihiko, Hirose, Masaya, Saji, Tomomi, Ushikubi, Fumitaka, Matsuoka, Toshiyuki, Noda, Yoichi, Tanaka, Takashi, Yoshida, Nobuaki, Narumiya, Shuh, Ichikawa, Atsushi
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1999
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17918/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10468638/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.18.10501
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