Abortive expansion of the cumulus and impaired fertility in mice lacking the prostaglandin E receptor subtype EP(2)

Female mice lacking the gene encoding the prostaglandin (PG) E(2) receptor subtype EP(2) (EP(2)(−/−)) become pregnant and deliver their pups at term, but with a much reduced litter size. A decrease in ovulation number and a much reduced fertilization rate were observed in EP(2)(−/−) females without...

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Detalhes bibliográficos
Main Authors: Hizaki, Hiroko, Segi, Eri, Sugimoto, Yukihiko, Hirose, Masaya, Saji, Tomomi, Ushikubi, Fumitaka, Matsuoka, Toshiyuki, Noda, Yoichi, Tanaka, Takashi, Yoshida, Nobuaki, Narumiya, Shuh, Ichikawa, Atsushi
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC17918/
https://ncbi.nlm.nih.gov/pubmed/10468638
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