Ciliary neurotrophic factor corrects obesity and diabetes associated with leptin deficiency and resistance

Receptor subunits for the neurocytokine ciliary neurotrophic factor (CNTF) share sequence similarity with the receptor for leptin, an adipocyte-derived cytokine involved in body weight homeostasis. We report here that CNTF and leptin activate a similar pattern of STAT factors in neuronal cells, and...

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Bibliografiska uppgifter
Huvudupphovsmän: Gloaguen, Isabelle, Costa, Patrizia, Demartis, Anna, Lazzaro, Domenico, Di Marco, Annalise, Graziani, Rita, Paonessa, Giacomo, Chen, Fang, Rosenblum, Charles I., Van der Ploeg, Lex H. T., Cortese, Riccardo, Ciliberto, Gennaro, Laufer, Ralph
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences of the USA 1997
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC21071/
https://ncbi.nlm.nih.gov/pubmed/9177239
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