Development of Animal Models for Adeno-Associated Virus Site-Specific Integration

The adeno-associated virus (AAV) is unique in its ability to target viral DNA integration to a defined region of human chromosome 19 (AAVS1). Since AAVS1 sequences are not conserved in a rodent’s genome, no animal model is currently available to study AAV-mediated site-specific integration. We descr...

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Bibliographic Details
Main Authors:	Rizzuto, Gabriella, Gorgoni, Barbara, Cappelletti, Manuela, Lazzaro, Domenico, Gloaguen, Isabelle, Poli, Valeria, Sgura, Antonella, Cimini, Daniela, Ciliberto, Gennaro, Cortese, Riccardo, Fattori, Elena, La Monica, Nicola
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology 1999
Subjects:	Gene Therapy
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC104499/ https://ncbi.nlm.nih.gov/pubmed/9971837
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Development of Animal Models for Adeno-Associated Virus Site-Specific Integration

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