Ciliary neurotrophic factor corrects obesity and diabetes associated with leptin deficiency and resistance

Receptor subunits for the neurocytokine ciliary neurotrophic factor (CNTF) share sequence similarity with the receptor for leptin, an adipocyte-derived cytokine involved in body weight homeostasis. We report here that CNTF and leptin activate a similar pattern of STAT factors in neuronal cells, and...

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Detalhes bibliográficos
Main Authors: Gloaguen, Isabelle, Costa, Patrizia, Demartis, Anna, Lazzaro, Domenico, Di Marco, Annalise, Graziani, Rita, Paonessa, Giacomo, Chen, Fang, Rosenblum, Charles I., Van der Ploeg, Lex H. T., Cortese, Riccardo, Ciliberto, Gennaro, Laufer, Ralph
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC21071/
https://ncbi.nlm.nih.gov/pubmed/9177239
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