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Development of Animal Models for Adeno-Associated Virus Site-Specific Integration

The adeno-associated virus (AAV) is unique in its ability to target viral DNA integration to a defined region of human chromosome 19 (AAVS1). Since AAVS1 sequences are not conserved in a rodent’s genome, no animal model is currently available to study AAV-mediated site-specific integration. We descr...

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Udgivet i:J Virol
Principais autores: Rizzuto, Gabriella, Gorgoni, Barbara, Cappelletti, Manuela, Lazzaro, Domenico, Gloaguen, Isabelle, Poli, Valeria, Sgura, Antonella, Cimini, Daniela, Ciliberto, Gennaro, Cortese, Riccardo, Fattori, Elena, La Monica, Nicola
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1999
Fag:
Gene Therapy
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104499/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9971837/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.3.2517-2526.1999
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