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Conjugation of a self-antigen to papillomavirus-like particles allows for efficient induction of protective autoantibodies

High avidity and long-lasting autoantibodies to a self-polypeptide (TNF-α) were generated after parenteral vaccination of mice with low doses of virus-like particle–based (VLP-based) vaccines that were constructed by linking mouse TNF-α peptides to the surface of papillomavirus VLPs. High-titer auto...

詳細記述

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書誌詳細
出版年:J Clin Invest
主要な著者: Chackerian, Bryce, Lowy, Douglas R., Schiller, John T.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC209354/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11489935/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI11849
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