The CCR5 receptor acts as an alloantigen in CCR5Δ32 homozygous individuals: Identification of chemokineand HIV-1-blocking human antibodies

The chemokine receptor CCR5 is the major coreceptor for infection by macrophage-tropic R5 HIV-1. A 32-bp deletion in the gene coding for CCR5 (CCR5Δ32) occurs with a frequency of 10% in the Caucasian population and results in a receptor protein that is truncated and not expressed at the cell surface...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Ditzel, Henrik J., Rosenkilde, Mette M., Garred, Peter, Wang, Meng, Koefoed, Klaus, Pedersen, Court, Burton, Dennis R., Schwartz, Thue W.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1998
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20245/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9560260/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.9.5241
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