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Chimeric papillomavirus virus-like particles elicit antitumor immunity against the E7 oncoprotein in an HPV16 tumor model

Papillomavirus-like particles (VLPs) are a promising prophylactic vaccine candidate to prevent human papillomavirus (HPV) infections and associated epithelial neoplasia. However, they are unlikely to have therapeutic effects because the virion capsid proteins are not detected in the proliferating ce...

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Detalhes bibliográficos
Main Authors: Greenstone, Heather L., Nieland, John D., de Visser, Karin E., De Bruijn, Marloes L. H., Kirnbauer, Reinhard, Roden, Richard B. S., Lowy, Douglas R., Kast, W. Martin, Schiller, John T.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC19193/
https://ncbi.nlm.nih.gov/pubmed/9465097
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