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Chimeric papillomavirus virus-like particles elicit antitumor immunity against the E7 oncoprotein in an HPV16 tumor model

Papillomavirus-like particles (VLPs) are a promising prophylactic vaccine candidate to prevent human papillomavirus (HPV) infections and associated epithelial neoplasia. However, they are unlikely to have therapeutic effects because the virion capsid proteins are not detected in the proliferating ce...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Greenstone, Heather L., Nieland, John D., de Visser, Karin E., De Bruijn, Marloes L. H., Kirnbauer, Reinhard, Roden, Richard B. S., Lowy, Douglas R., Kast, W. Martin, Schiller, John T.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1998
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19193/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9465097/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.4.1800
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