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Prion Protein Expression Differences in Microglia and Astroglia Influence Scrapie-Induced Neurodegeneration in the Retina and Brain of Transgenic Mice

Activated microglia and astroglia are known to be involved in a variety of neurodegenerative diseases, including prion diseases. In the present experiments, we studied activation of astroglia and microglia after intraocular scrapie infection in transgenic mice expressing prion protein (PrP) in multi...

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Bibliographische Detailangaben
Hauptverfasser: Kercher, Lisa, Favara, Cynthia, Striebel, James F., LaCasse, Rachel, Chesebro, Bruce
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045503/
https://ncbi.nlm.nih.gov/pubmed/17652390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00865-07
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