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Prion Protein Expression Differences in Microglia and Astroglia Influence Scrapie-Induced Neurodegeneration in the Retina and Brain of Transgenic Mice

Activated microglia and astroglia are known to be involved in a variety of neurodegenerative diseases, including prion diseases. In the present experiments, we studied activation of astroglia and microglia after intraocular scrapie infection in transgenic mice expressing prion protein (PrP) in multi...

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Bibliografische gegevens
Hoofdauteurs: Kercher, Lisa, Favara, Cynthia, Striebel, James F., LaCasse, Rachel, Chesebro, Bruce
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045503/
https://ncbi.nlm.nih.gov/pubmed/17652390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00865-07
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