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Familial Alzheimer's disease mutations alter the stability of the amyloid β-protein monomer folding nucleus
Amyloid β-protein (Aβ) oligomers may be the proximate neurotoxins in Alzheimer's disease (AD). Recently, to elucidate the oligomerization pathway, we studied Aβ monomer folding and identified a decapeptide segment of Aβ, (21)Ala–(22)Glu–(23)Asp–(24)Val–(25)Gly–(26)Ser–(27)Asn–(28)Lys–(29)Gly–(3...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2034231/ https://ncbi.nlm.nih.gov/pubmed/17940047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705197104 |
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