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Effects of familial mutations on the folding nucleation of the Alzheimer Amyloid β-protein
The effect of single amino acid substitutions associated with the Italian (E22K), Arctic (E22G), Dutch (E22Q) and Iowa (D23N) familial forms of Alzheimer’s disease (AD) and cerebral amyloid angiopathy on the structure of the 21-30 fragment of the Alzheimer amyloid β-protein (Aβ) is investigated usin...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2597412/ https://ncbi.nlm.nih.gov/pubmed/18597778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.05.069 |
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