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Amyloid β-protein monomer structure: A computational and experimental study

The structural properties of the Aβ42 peptide, a main constituent of the amyloid plaques formed in Alzheimer’s disease, were investigated through a combination of ion-mobility mass spectrometry and theoretical modeling. Replica exchange molecular dynamics simulations using a fully atomic description...

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Hlavní autoři: Baumketner, Andrij, Bernstein, Summer L., Wyttenbach, Thomas, Bitan, Gal, Teplow, David B., Bowers, Michael T., Shea, Joan-Emma
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2249763/
https://ncbi.nlm.nih.gov/pubmed/16501222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051762406
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