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Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer’s disease

In recent years, small protein oligomers have been implicated in the aetiology of a number of important amyloid diseases, such as type 2 diabetes, Parkinson’s disease and Alzheimer’s disease. As a consequence, research efforts are being directed away from traditional targets, such as amyloid plaques...

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Detalhes bibliográficos
Main Authors: Bernstein, Summer L., Dupuis, Nicholas F., Lazo, Noel D., Wyttenbach, Thomas, Condron, Margaret M., Bitan, Gal, Teplow, David B., Shea, Joan-Emma, Ruotolo, Brandon T., Robinson, Carol V., Bowers, Michael T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918915/
https://ncbi.nlm.nih.gov/pubmed/20703363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.247
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