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Amyloid β-Protein Assembly as a Therapeutic Target of Alzheimer’s Disease
Alzheimer’s disease (AD), the most common neurodegenerative disorder in the aged, is characterized by the cerebral deposition of fibrils formed by the amyloid β-protein (Aβ), a 40–42 amino acid peptide. The folding of Aβ into neurotoxic oligomeric, protofibrillar, and fibrillar assemblies is hypothe...
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| Publicado no: | Curr Pharm Des |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5650911/ https://ncbi.nlm.nih.gov/pubmed/19075703 |
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