SPATIAL AND FUNCTIONAL RELATIONSHIP BETWEEN POLY(ADP-RIBOSE) POLYMERASE-1 AND POLY(ADP-RIBOSE) GLYCOHYDROLASE IN THE BRAIN

Poly(ADP-ribose) polymerases (PARPs) are members of a family of enzymes that utilize NAD(+) as substrate to form large ADP-ribose polymers (PAR) in the nucleus. PAR has a very short half life due to its rapid degradation by poly(ADP-ribose) glycohydrolase (PARG). PARP-1 mediates acute neuronal cell...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Poitras, Marc F., Koh, David W., Yu, Seong-Woon, Andrabi, Shaida A., Mandir, Allen S., Poirier, Guy G., Dawson, Valina L., Dawson, Ted M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2007
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000859/
https://ncbi.nlm.nih.gov/pubmed/17640816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2007.04.062
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