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Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death
Apoptosis-inducing factor (AIF), a mitochondrial oxidoreductase, is released into the cytoplasm to induce cell death in response to poly(ADP-ribose) (PAR) polymerase-1 (PARP-1) activation. How PARP-1 activation leads to AIF release is not known. Here we identify PAR polymer as a cell death signal th...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1838748/ https://ncbi.nlm.nih.gov/pubmed/17116881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606528103 |
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