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Phosphorothioate cap analogs stabilize mRNA and increase translational efficiency in mammalian cells
Capped RNAs synthesized by in vitro transcription have found wide utility for studying mRNA function and metabolism and for producing proteins of interest. We characterize here a recently synthesized series of cap analogs with improved properties that contain a sulfur substitution for a nonbridging...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1986804/ https://ncbi.nlm.nih.gov/pubmed/17720878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.701307 |
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