Synthesis and characterization of mRNA cap analogs containing phosphorothioate substitutions that bind tightly to eIF4E and are resistant to the decapping pyrophosphatase DcpS

Analogs of the mRNA cap are widely employed to study processes involved in mRNA metabolism as well as being useful in biotechnology and medicinal applications. Here we describe synthesis of six dinucleotide cap analogs bearing a single phosphorothioate modification at either the α, β, or γ position...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Kowalska, Joanna, Lewdorowicz, Magdalena, Zuberek, Joanna, Grudzien-Nogalska, Ewa, Bojarska, Elzbieta, Stepinski, Janusz, Rhoads, Robert E., Darzynkiewicz, Edward, Davis, Richard E., Jemielity, Jacek
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2008
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2390807/
https://ncbi.nlm.nih.gov/pubmed/18430890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.990208
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller