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Structural insights into the recognition of substrates and activators by the OSR1 kinase
The oxidative-stress-responsive kinase 1 (OSR1) and the STE20/SPS1-related proline/alanine-rich kinase (SPAK) are key enzymes in a signalling cascade regulating the activity of Na(+)/K(+)/2Cl(−) co-transporters (NKCCs) in response to osmotic stress. Both kinases have a conserved carboxy-terminal (CC...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1973955/ https://ncbi.nlm.nih.gov/pubmed/17721439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7401048 |
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