Regulation of activity and localization of the WNK1 protein kinase by hyperosmotic stress

Eitemau Tebyg

• SPAK/OSR1 regulate NKCC1 and WNK activity: analysis of WNK isoform interactions and activation by T-loop trans-autophosphorylation
  gan: Thastrup, Jacob O., et al.
  Cyhoeddwyd: (2011)
• Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1
  gan: Vitari, Alberto C., et al.
  Cyhoeddwyd: (2006)
• The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases
  gan: Vitari, Alberto C., et al.
  Cyhoeddwyd: (2005)
• WNK1, the kinase mutated in an inherited high-blood-pressure syndrome, is a novel PKB (protein kinase B)/Akt substrate.
  gan: Vitari, Alberto C, et al.
  Cyhoeddwyd: (2004)
• Identification and characterization of four novel phosphorylation sites (Ser31, Ser325, Thr336 and Thr366) on LKB1/STK11, the protein kinase mutated in Peutz-Jeghers cancer syndrome.
  gan: Sapkota, Gopal P, et al.
  Cyhoeddwyd: (2002)