WNK1, the kinase mutated in an inherited high-blood-pressure syndrome, is a novel PKB (protein kinase B)/Akt substrate.

Recent evidence indicates that mutations in the gene encoding the WNK1 [with no K (lysine) protein kinase-1] results in an inherited hypertension syndrome called pseudohypoaldosteronism type II. The mechanisms by which WNK1 is regulated or the substrates it phosphorylates are currently unknown. We n...

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Sonraí Bibleagrafaíochta
Main Authors: Vitari, Alberto C, Deak, Maria, Collins, Barry J, Morrice, Nick, Prescott, Alan R, Phelan, Anne, Humphreys, Sian, Alessi, Dario R
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2004
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223938/
https://ncbi.nlm.nih.gov/pubmed/14611643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031692
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