WNK1, the kinase mutated in an inherited high-blood-pressure syndrome, is a novel PKB (protein kinase B)/Akt substrate.

Recent evidence indicates that mutations in the gene encoding the WNK1 [with no K (lysine) protein kinase-1] results in an inherited hypertension syndrome called pseudohypoaldosteronism type II. The mechanisms by which WNK1 is regulated or the substrates it phosphorylates are currently unknown. We n...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Vitari, Alberto C, Deak, Maria, Collins, Barry J, Morrice, Nick, Prescott, Alan R, Phelan, Anne, Humphreys, Sian, Alessi, Dario R
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2004
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223938/
https://ncbi.nlm.nih.gov/pubmed/14611643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031692
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk