Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice

Apolipoprotein (apo) E4 increases the risk and accelerates the onset of Alzheimer's disease (AD). However, the underlying mechanisms remain to be determined. We previously found that apoE undergoes proteolytic cleavage in AD brains and in cultured neuronal cells, resulting in the accumulation o...

詳細記述

保存先:
書誌詳細
主要な著者: Harris, Faith M., Brecht, Walter J., Xu, Qin, Tesseur, Ina, Kekonius, Lisa, Wyss-Coray, Tony, Fish, Jo Dee, Masliah, Eliezer, Hopkins, Paul C., Scearce-Levie, Kimberly, Weisgraber, Karl H., Mucke, Lennart, Mahley, Robert W., Huang, Yadong
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2003
主題:
Biological Sciences
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC196910/
https://ncbi.nlm.nih.gov/pubmed/12939405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1434398100
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料