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Development of a high-throughput screen for soluble epoxide hydrolase inhibition
Mammalian soluble epoxide hydrolase (sEH) represents a highly promising new target for drug development. Chemical inhibition of this enzyme in animal models was shown to treat hypertension and vascular inflammation as well as related syndromes. Existing sEH inhibitors are relatively potent and speci...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2006
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1964503/ https://ncbi.nlm.nih.gov/pubmed/16729954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2006.04.045 |
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