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Inhibition of soluble epoxide hydrolase by fulvestrant and sulfoxides
The soluble epoxide hydrolase (sEH) is a key enzyme in the metabolism of epoxy-fatty acids, signaling molecules involved in numerous biologies. Toward finding novel inhibitors of sEH, a library of known drugs was tested for inhibition of sEH. We found that fulvestrant, an anticancer agent, is a pote...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3703951/ https://ncbi.nlm.nih.gov/pubmed/23684894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.04.083 |
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