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Pharmacokinetic Screening of Soluble Epoxide Hydrolase Inhibitors in Dogs
Epoxyeicosatrienoic acids that have anti-hypertensive and anti-inflammatory properties are mainly metabolized by soluble epoxide hydrolase (sEH, EC 3.3.2.3). Therefore, sEH has emerged as a therapeutic target for treating various cardiovascular diseases and inflammatory pain. N,N’-Disubstituted urea...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3285443/ https://ncbi.nlm.nih.gov/pubmed/20359531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejps.2010.03.018 |
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