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Development of a high-throughput screen for soluble epoxide hydrolase inhibition

Mammalian soluble epoxide hydrolase (sEH) represents a highly promising new target for drug development. Chemical inhibition of this enzyme in animal models was shown to treat hypertension and vascular inflammation as well as related syndromes. Existing sEH inhibitors are relatively potent and speci...

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Detaylı Bibliyografya
Asıl Yazarlar: Wolf, Nicola M., Morisseau, Christophe, Jones, Paul D., Hock, Bertold, Hammock, Bruce D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2006
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1964503/
https://ncbi.nlm.nih.gov/pubmed/16729954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2006.04.045
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