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Development of a high-throughput screen for soluble epoxide hydrolase inhibition
Mammalian soluble epoxide hydrolase (sEH) represents a highly promising new target for drug development. Chemical inhibition of this enzyme in animal models was shown to treat hypertension and vascular inflammation as well as related syndromes. Existing sEH inhibitors are relatively potent and speci...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1964503/ https://ncbi.nlm.nih.gov/pubmed/16729954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2006.04.045 |
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