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Fluorescent substrates for soluble epoxide hydrolase and application to inhibition studies
Inhibition of the mammalian soluble epoxide hydrolase (sEH) is a promising new therapy in the treatment of disorders resulting from hypertension and vascular inflammation. A spectrophotometric assay (4-nitrophenyl-trans-2,3-epoxy-3-phenylpropyl carbonate, NEPC) is currently used to screen libraries...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1447601/ https://ncbi.nlm.nih.gov/pubmed/15963942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2005.03.041 |
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