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Attenuation of cisplatin nephrotoxicity by inhibition of soluble epoxide hydrolase

Cisplatin is a highly effective chemotherapeutic agent against many tumors; however, it is also a potent nephrotoxicant. Given that there have been no significant advances in our ability to clinically manage acute renal failure since the advent of dialysis, the development of novel strategies to abl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Parrish, Alan R., Chen, Gang, Burghardt, Robert C., Watanabe, Takaho, Morisseau, Christophe, Hammock, Bruce D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033346/
https://ncbi.nlm.nih.gov/pubmed/18386137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10565-008-9071-0
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