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Attenuation of cisplatin nephrotoxicity by inhibition of soluble epoxide hydrolase

Cisplatin is a highly effective chemotherapeutic agent against many tumors; however, it is also a potent nephrotoxicant. Given that there have been no significant advances in our ability to clinically manage acute renal failure since the advent of dialysis, the development of novel strategies to abl...

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Main Authors: Parrish, Alan R., Chen, Gang, Burghardt, Robert C., Watanabe, Takaho, Morisseau, Christophe, Hammock, Bruce D.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033346/
https://ncbi.nlm.nih.gov/pubmed/18386137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10565-008-9071-0
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