Inhibition of the Soluble Epoxide Hydrolase by Tyrosine Nitration

Inhibition of the soluble epoxide hydrolase (sEH) has beneficial effects on vascular inflammation and hypertension indicating that the enzyme may be a promising target for drug development. As the enzymatic core of the hydrolase domain of the human sEH contains two tyrosine residues (Tyr(383) and Ty...

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Autores principales: Barbosa-Sicard, Eduardo, Frömel, Timo, Keserü, Benjamin, Brandes, Ralf P., Morisseau, Christophe, Hammock, Bruce D., Braun, Thomas, Krüger, Marcus, Fleming, Ingrid
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Protein Synthesis, Post-Translational Modification, and Degradation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788866/
https://ncbi.nlm.nih.gov/pubmed/19704161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.054759
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