Molecular Umbrellas: a Novel Class of Candidate Topical Microbicides To Prevent Human Immunodeficiency Virus and Herpes Simplex Virus Infections

Molecular umbrella compounds may function as novel topical microbicides to prevent human immunodeficiency virus (HIV) and herpes simplex virus (HSV) infections. In a preliminary structure-activity investigation, one umbrella compound, designated Spm8CHAS, was identified which inhibited both HIV and...

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Dettagli Bibliografici
Autori principali: Madan, Rebecca Pellett, Mesquita, Pedro M. M., Cheshenko, Natalia, Jing, Bingwen, Shende, Vikas, Guzman, Esmeralda, Heald, Taylor, Keller, Marla J., Regen, Steven L., Shattock, Robin J., Herold, Betsy C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2007
Soggetti:
Vaccines and Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933367/
https://ncbi.nlm.nih.gov/pubmed/17494078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02851-06
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