Molecular Umbrellas: a Novel Class of Candidate Topical Microbicides To Prevent Human Immunodeficiency Virus and Herpes Simplex Virus Infections

Molecular umbrella compounds may function as novel topical microbicides to prevent human immunodeficiency virus (HIV) and herpes simplex virus (HSV) infections. In a preliminary structure-activity investigation, one umbrella compound, designated Spm8CHAS, was identified which inhibited both HIV and...

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Hlavní autoři: Madan, Rebecca Pellett, Mesquita, Pedro M. M., Cheshenko, Natalia, Jing, Bingwen, Shende, Vikas, Guzman, Esmeralda, Heald, Taylor, Keller, Marla J., Regen, Steven L., Shattock, Robin J., Herold, Betsy C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2007
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933367/
https://ncbi.nlm.nih.gov/pubmed/17494078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02851-06
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