Molecular Umbrellas: a Novel Class of Candidate Topical Microbicides To Prevent Human Immunodeficiency Virus and Herpes Simplex Virus Infections

Molecular umbrella compounds may function as novel topical microbicides to prevent human immunodeficiency virus (HIV) and herpes simplex virus (HSV) infections. In a preliminary structure-activity investigation, one umbrella compound, designated Spm8CHAS, was identified which inhibited both HIV and...

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Detalhes bibliográficos
Main Authors: Madan, Rebecca Pellett, Mesquita, Pedro M. M., Cheshenko, Natalia, Jing, Bingwen, Shende, Vikas, Guzman, Esmeralda, Heald, Taylor, Keller, Marla J., Regen, Steven L., Shattock, Robin J., Herold, Betsy C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933367/
https://ncbi.nlm.nih.gov/pubmed/17494078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02851-06
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