NP-1, a Rabbit α-Defensin, Prevents the Entry and Intercellular Spread of Herpes Simplex Virus Type 2

Rabbit neutrophil peptide-1 (NP-1), a prototypic α-defensin, protects cells in vitro from infection by clinical and laboratory isolates of herpes simplex virus type 2 (HSV-2). Incubation of concentrated virus stocks for 1 h with noncytotoxic concentrations of NP-1 reduces subsequent infection by >...

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Bibliografiska uppgifter
Huvudupphovsmän: Sinha, Sara, Cheshenko, Natalia, Lehrer, Robert I., Herold, Betsy C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2003
Ämnen:
Antiviral Agents
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC151743/
https://ncbi.nlm.nih.gov/pubmed/12543649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.2.494-500.2003
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