NP-1, a Rabbit α-Defensin, Prevents the Entry and Intercellular Spread of Herpes Simplex Virus Type 2

Rabbit neutrophil peptide-1 (NP-1), a prototypic α-defensin, protects cells in vitro from infection by clinical and laboratory isolates of herpes simplex virus type 2 (HSV-2). Incubation of concentrated virus stocks for 1 h with noncytotoxic concentrations of NP-1 reduces subsequent infection by >98...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Sinha, Sara, Cheshenko, Natalia, Lehrer, Robert I., Herold, Betsy C.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2003
Sujets:	Antiviral Agents
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151743/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12543649/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.2.494-500.2003
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