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Candidate Microbicide PPCM Blocks Human Immunodeficiency Virus Type 1 Infection in Cell and Tissue Cultures and Prevents Genital Herpes in a Murine Model

A structurally novel candidate microbicide, PPCM, which is formed from the reaction of d,l-mandelic acid with sulfuric acid, provides activity against human immunodeficiency virus (HIV) and herpes simplex virus (HSV) and is not cytotoxic. The objectives of the current studies were to comprehensively...

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Detalhes bibliográficos
Main Authors: Mesquita, Pedro M. M., Wilson, Sarah S., Manlow, Philippe, Fischetti, Lucia, Keller, Marla J., Herold, Betsy C., Shattock, Robin J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447100/
https://ncbi.nlm.nih.gov/pubmed/18434407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00335-08
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