Candidate Microbicide PPCM Blocks Human Immunodeficiency Virus Type 1 Infection in Cell and Tissue Cultures and Prevents Genital Herpes in a Murine Model

A structurally novel candidate microbicide, PPCM, which is formed from the reaction of d,l-mandelic acid with sulfuric acid, provides activity against human immunodeficiency virus (HIV) and herpes simplex virus (HSV) and is not cytotoxic. The objectives of the current studies were to comprehensively...

Full description

Saved in:
Bibliographic Details
Main Authors: Mesquita, Pedro M. M., Wilson, Sarah S., Manlow, Philippe, Fischetti, Lucia, Keller, Marla J., Herold, Betsy C., Shattock, Robin J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447100/
https://ncbi.nlm.nih.gov/pubmed/18434407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00335-08
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items