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Susceptibility to genital herpes as a biomarker predictive of increased HIV risk: expansion of a murine model of microbicide safety

BACKGROUND: A crucial gap in the development of microbicides for HIV prevention is the absence of models predictive of safety. Previous studies have demonstrated an increased susceptibility to genital herpes in mice following repeated applications of nonoxynol-9 (N-9). This study was designed to exp...

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Detalhes bibliográficos
Main Authors: Wilson, Sarah S, Cheshenko, Natalia, Fakioglu, Esra, Mesquita, Pedro MM, Keller, Marla J, Herold, Betsy C
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879645/
https://ncbi.nlm.nih.gov/pubmed/20032541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3851/IMP1463
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